Polycythemic response in normal adult rats to a nonprotein plasma extract from anemic rabbits.

作者: HENRY BORSOOK , ASHTON GRAYBIEL , GEOFFREY KEIGHLEY , EMANUEL WINDSOR

DOI: 10.1182/BLOOD.V9.7.734.734

关键词:

摘要: Experiments are described in which a protein-free extract of plasma obtained from anemic rabbits was injected into healthy young rats. The resulting erythropoietic response comparable to that induced by hypoxia. findings suggest humoral factor at work capable disturbing the physiologic mechanisms establish equilibrium between red blood cell formation and destruction. far-reaching significance these is apparent.

参考文章(6)
Henry Borsook, Clara L. Deasy, A.J. Haagen-Smit, Geoffrey Keighley, Peter H. Lowy, INCORPORATION IN VITRO OF LABELED AMINO ACIDS INTO PROTEINS OF RABBIT RETICULOCYTES Journal of Biological Chemistry. ,vol. 196, pp. 669- 694 ,(1952) , 10.1016/S0021-9258(19)52400-0
ALLAN ERSLEV, Humoral Regulation of Red Cell Production Blood. ,vol. 8, pp. 349- 357 ,(1953) , 10.1182/BLOOD.V8.4.349.349
David L. Drabkin, J. Harold Austin, SPECTROPHOTOMETRIC STUDIES I. SPECTROPHOTOMETRIC CONSTANTS FOR COMMON HEMOGLOBIN DERIVATIVES IN HUMAN, DOG, AND RABBIT BLOOD Journal of Biological Chemistry. ,vol. 98, pp. 719- 733 ,(1932) , 10.1016/S0021-9258(18)76122-X
Wilson C. Grant, Walter S. Root, Fundamental Stimulus for Erythropoiesis Physiological Reviews. ,vol. 32, pp. 449- 498 ,(1952) , 10.1152/PHYSREV.1952.32.4.449
C.M. Van Allen, An hematocrit method Journal of Laboratory and Clinical Medicine. ,vol. 10, pp. 1027- 1040 ,(1925) , 10.5555/URI:PII:S0022214325903125