A new irregular monoterpene acetate along with eight known compounds with antifungal potential from the aerial parts of Artemisia incisa Pamp (Asteraceae).

摘要: AbstractA new compound named as santolinylol-3-acetate (4-(2-hydroxypropan-2-yl)-2-methylhexa-1,5-dien-3-yl acetate) (3), along with seven known compounds; linoleic acid (1), benzoic (2), santolinylol (4), ethyl-(E)-p-hydroxy cinnamate (5), scopoletin (6), esculetin (7) isofraxidin (8) and eupatorin (9), were isolated from the aerial parts (ethanolic extract) of endangered species: Artemisia incisa Pamp (Asteraceae). The compounds’ structures determined through modern spectroscopic techniques, comparison data (physicochemical constants) literature. relative stereochemistry (3) was by comparing its NOESY, specific rotation diol analogue; same plant; A. incisa. results antifungal activity showed that coumarins are whole less active compounds. Compounds 3 (25 300 μg/mL), 4 (12.5 good activities against Candida albicans, Aspergillus flavus...