Synthesis of functional polyester for fabrication of nano-fibrous scaffolds and its effect on PC12 cells
作者： Na Qiang , Shuo Tang , Xiao-jun Shi , Hao Li , Yi-hong Ma
DOI: 10.1080/09205063.2015.1114308
关键词:
摘要: AbstractAn ideal scaffold should mimic the advantageous characteristics of a natural extracellular matrix for cell attachment, proliferation, and differentiation. In this study, well-defined block copolymer with functional groups was synthesized. The structure characterized by nuclear magnetic resonance, gel permeation chromatography, differential scanning calorimetry. Thermally induced phase separation employed to fabricate nano-fibrous scaffolds based on synthesized copolymer. scaffold, fiber diameter ranging from 400 500 nm, fabricated in vitro culture PC12 cells. carboxyl side chain resulted increased hydrophilicity enhanced proliferation. addition, beneficial directing growth regenerating axons nerve tissue engineering. Results 3-(4,5-dimethylthiazol-2yl)-2,5-diphenyltetrazolium bromide (MTT) assay electron microscopy c...
sci-hub.se 参考文章(29)
Rosa Akbarzadeh, Azizeh-Mitra Yousefi, Effects of processing parameters in thermally induced phase separation technique on porous architecture of scaffolds for bone tissue engineering. Journal of Biomedical Materials Research Part B. ,vol. 102, pp. 1304- 1315 ,(2014) , 10.1002/JBM.B.33101
Laura Koepsell, Tyler Remund, Jing Bao, Daniel Neufeld, Hao Fong, Ying Deng, Tissue engineering of annulus fibrosus using electrospun fibrous scaffolds with aligned polycaprolactone fibers Journal of Biomedical Materials Research Part A. ,vol. 99, pp. 564- 575 ,(2011) , 10.1002/JBM.A.33216
Kyung Mi Woo, Ji-Hae Jun, Victor J. Chen, Jihye Seo, Jeong-Hwa Baek, Hyun-Mo Ryoo, Gwan-Shik Kim, Martha J. Somerman, Peter X. Ma, Nano-fibrous scaffolding promotes osteoblast differentiation and biomineralization. Biomaterials. ,vol. 28, pp. 335- 343 ,(2007) , 10.1016/J.BIOMATERIALS.2006.06.013
Mei Zhang, Yongjia Liu, Yuqing Jia, Hongshuang Han, Dahui Sun, Preparation and Evaluation of Electrospun Zein/HA Fibers Based on Two Methods of Adding HA Nanoparticles Journal of Bionic Engineering. ,vol. 11, pp. 115- 124 ,(2014) , 10.1016/S1672-6529(14)60026-3
Hajar Seyednejad, Wei Ji, Wouter Schuurman, Wouter J. A. Dhert, Jos Malda, Fang Yang, John A. Jansen, Cornelus van Nostrum, Tina Vermonden, Wim E. Hennink, An electrospun degradable scaffold based on a novel hydrophilic polyester for tissue-engineering applications. Macromolecular Bioscience. ,vol. 11, pp. 1684- 1692 ,(2011) , 10.1002/MABI.201100229
Erde Can, Gokce Udenir, Ayse Irem Kanneci, Gamze Kose, Seyda Bucak, Investigation of PLLA/PCL Blends and Paclitaxel Release Profiles Aaps Pharmscitech. ,vol. 12, pp. 1442- 1453 ,(2011) , 10.1208/S12249-011-9714-Y
T. Corrales, I. Larraza, F. Catalina, T. Portolés, C. Ramírez-Santillán, M. Matesanz, C. Abrusci, In Vitro Biocompatibility and Antimicrobial Activity of Poly(ε-caprolactone)/Montmorillonite Nanocomposites Biomacromolecules. ,vol. 13, pp. 4247- 4256 ,(2012) , 10.1021/BM301537G
Annasara Hansson, Tiziana Di Francesco, Françoise Falson, Patricia Rousselle, Olivier Jordan, Gerrit Borchard, Preparation and evaluation of nanoparticles for directed tissue engineering. International Journal of Pharmaceutics. ,vol. 439, pp. 73- 80 ,(2012) , 10.1016/J.IJPHARM.2012.09.053
Murali Ragothaman, Thanikaivelan Palanisamy, Cheirmadurai Kalirajan, Collagen-poly(dialdehyde) guar gum based porous 3D scaffolds immobilized with growth factor for tissue engineering applications. Carbohydrate Polymers. ,vol. 114, pp. 399- 406 ,(2014) , 10.1016/J.CARBPOL.2014.08.045
Chao Zhang, Yun-Yu Hu, Fu-Zhai Cui, Shu-Ming Zhang, Di-Ke Ruan, A study on a tissue-engineered bone using rhBMP-2 induced periosteal cells with a porous nano-hydroxyapatite/collagen/poly(L-lactic acid) scaffold Biomedical Materials. ,vol. 1, pp. 56- 62 ,(2006) , 10.1088/1748-6041/1/2/002