Leukocyte 5′-Nucleotidase

摘要: The 5′-mononucleotides are dephosphorylated by the enzyme, 5′-ribonucleotide phosphohydrolase (EC 3.1.3.5), commonly known as 5′-nucleotidase (5′N). This enzyme was first described Reis (1937, 1939) in heart and skeletal muscle its specificity established histochemically for 5′-nucleotides Gomori (1949a,b). activity has since been many tissues (Drummond Yamamoto, 1971). review of 5′N mammalian leukocytes is divided into two parts. part deals with properties. Studies on from sources other than included much early knowledge derived tissues. second part, which discusses leukocyte 5′N, will attempt to resolve conflicting reports presence or absence particular types white cells. In addition, effects hematologic disorders summarized.