Sagittal sinus blood flow in the ovine fetus as a continuous measure of cerebral blood flow: relationship to behavioural state activity

摘要: Abstract Superior sagittal sinus blood flow ( Q ss ) was studied over a 6-h period in nine chronically catheterized fetal sheep as continuous measure of cerebral to determine the change values and measures variability relation behavioural state activity. Mean increased during low voltage (LV)/rapid eye movement (REM) compared high (HV)/NREM by ∼25%, further periods LV/REM with breathing movements. The increase abrupt began at transition LV/REM, rate 2-fold greater than that HV/NREM, where decrease gradual prior evident change. showed considerable fluctuation, which tended be HV/NREM when analyzed using longer term variability. thus provides for ovine fetus, ∼25% from similar previously reported radioactive microspheres. versus before would suggest state-related brain is better linked presence LV electrocorticogram favours its active generation.