Use of SSRIs among Danish children: a nationwide study.

作者: Anton Pottegård , Helga Zoëga , Jesper Hallas , Per Damkier

DOI: 10.1007/S00787-014-0523-1

关键词:

摘要: Our objective was to describe the use of selective serotonin reuptake inhibitors (SSRIs) in entire Danish population children and adolescents from 1995 2011. Data on filled SSRIs were obtained for all Denmark aged 5–17 during 1995–2011. The amount type calculated as well incidence rates prevalence proportions. Furthermore, we looked at concurrent other psychotropic drug treatment duration. A total 23,547 used study period, most commonly sertraline followed by citalopram. Overall, rate increased 0.57 per 1,000 person years 1997 3.30 2010 fell 2.55 2011, while proportion rose 0.1 end 3.3 However, these findings driven entirely an increase among (12–17 years), where 0.11 0.36 4.64 8.52 boys girls, respectively. significant SSRI users drugs concurrently, notably antipsychotics (12–28 %) psychostimulants (10–33 %). About 50 % 40 discontinued within 12 months initiation. We found a marked between Whether this reflects true disorder occurrence, diagnostic intensity or more aggressive remains uncertain.

参考文章(37)
L. Frank, Epidemiology. When an entire country is a cohort. Science. ,vol. 287, pp. 2398- 2399 ,(2000) , 10.1126/SCIENCE.287.5462.2398
Euni Lee, Anna R. Teschemaker, Rosemary Johann-Liang, Gina Bazemore, Martin Yoon, Kye-Sik Shim, Marlon Daniel, Jerome Pittman, Anthony K. Wutoh, Off-label prescribing patterns of antidepressants in children and adolescents. Pharmacoepidemiology and Drug Safety. ,vol. 21, pp. 137- 144 ,(2012) , 10.1002/PDS.2145
Helga Zoëga, Gísli Baldursson, Birgir Hrafnkelsson, Anna Birna Almarsdóttir, Unnur Valdimarsdóttir, Matthías Halldórsson, Psychotropic drug use among Icelandic children: a nationwide population-based study. Journal of Child and Adolescent Psychopharmacology. ,vol. 19, pp. 757- 764 ,(2009) , 10.1089/CAP.2009.0003
Jonathan S. Comer, Mark Olfson, Ramin Mojtabai, National trends in child and adolescent psychotropic polypharmacy in office-based practice, 1996-2007 Journal of the American Academy of Child and Adolescent Psychiatry. ,vol. 49, pp. 1001- 1010 ,(2010) , 10.1016/J.JAAC.2010.07.007
M Koelch, A Prestel, H Singer, F Keller, Jörg M Fegert, R Schlack, H Hoelling, H Knopf, None, Psychotropic medication in children and adolescents in Germany: prevalence, indications, and psychopathological patterns. Journal of Child and Adolescent Psychopharmacology. ,vol. 19, pp. 765- 770 ,(2009) , 10.1089/CAP.2009.0018
Barbara Geller, Rebecca Tillman, Kristine Bolhofner, Betsy Zimerman, Pharmacological and non-drug treatment of child bipolar I disorder during prospective eight-year follow-up. Bipolar Disorders. ,vol. 12, pp. 164- 171 ,(2010) , 10.1111/J.1399-5618.2010.00791.X
Barbara Hoff Esbjørn, Mette Hoeyer, Jørgen Dyrborg, Ingrid Leth, Philip C. Kendall, Prevalence and co-morbidity among anxiety disorders in a national cohort of psychiatrically referred children and adolescents Journal of Anxiety Disorders. ,vol. 24, pp. 866- 872 ,(2010) , 10.1016/J.JANXDIS.2010.06.009
Benedetto Vitiello, Susan Swedo, Antidepressant Medications in Children The New England Journal of Medicine. ,vol. 350, pp. 1489- 1491 ,(2004) , 10.1056/NEJMP038248
Leena K. Saastamoinen, Mika Wallin, Piia Lavikainen, Marja S. Airaksinen, Andre Sourander, J. Simon Bell, Treatment duration with selective serotonin reuptake inhibitors among children and adolescents in Finland: a nationwide register study. European Journal of Clinical Pharmacology. ,vol. 68, pp. 1109- 1117 ,(2012) , 10.1007/S00228-012-1233-6