Ventricular conduction abnormalities as predictors of long‐term survival in acute de novo and decompensated chronic heart failure

摘要: Aims Data on the prognostic role of left and right bundle branch blocks (LBBB RBBB), nonspecific intraventricular conduction delay (IVCD; QRS 110 ms, no BBB) in acute heart failure (AHF) are controversial. Our aim was to investigate electrocardiographic predictors long-term survival in patients with de novo AHF acutely decompensated chronic heart failure (ADCHF). Methods Results We analysed the admission electrocardiogram 982 patients from a multicenter European cohort 3.9 years’ mean follow-up. Half (51.5%, n = 506) had AHF. LBBB, and IVCD were more common ADCHF than AHF: 17.2% vs. 8.7% (P 0.001) 20.6% vs. 13.2% 0.001), respectively, and RBBB almost equally (6.9% 8.1%; P 0.5), respectively. Mortality during follow-up higher (85.4%) IVCD (73.7%) compared with patients normal ventricular conduction (57.0%); P<0.001 for both. The impact prognosis prominent de novo (adjusted HR 1.93, 1.03–3.60; 0.04), IVCD independently predicted death 1.79, 1.28–2.52; 0.001). Both findings pronounced reduced ejection fraction. LBBB showed no association increased mortality either the subgroups. main results confirmed validation cohort 1511 5.9 follow-up. Conclusions Conduction abnormalities predict survival differently ADCHF. predicts mortality in AHF, has additive predictive value requiring hospitalization.