Prognostic Implication of Ventricular Conduction Disturbance Pattern in Hospitalized Patients with Acute Heart Failure Syndrome.

摘要: BACKGROUND AND OBJECTIVES Conflicting data exist regarding the prognostic implication of ventricular conduction disturbance pattern in patients with heart failure (HF). This study investigated impact hospitalized acute HF. METHODS Data from Korean Acute Heart Failure registry were used. Patients categorized into four groups: narrow QRS (<120 ms), right bundle branch block (RBBB), left (LBBB), and nonspecific intraventricular delay (NICD). The NICD was defined as prolonged (≥120 ms) without typical features LBBB or RBBB. primary endpoint composite all-cause mortality rehospitalization for HF aggravation within 1 year after discharge. RESULTS included 5,157 patients. occurred 39.7% population. group showed highest incidence followed by NICD, RBBB, groups (52.5% vs. 49.7% 44.4% 37.5%, p<0.001). In a multivariable Cox-proportional hazards regression analysis, associated 39% 28% increased risk (LBBB hazard ratio [HR], 1.392; 95% confidence interval [CI], 1.152-1.681; HR, 1.278; CI, 1.074-1.520) compared group. HR RBBB 1.103 (95% 0.915-1.329). CONCLUSIONS independently an 1-year adverse event HF, whereas impacts limited. TRIAL REGISTRATION ClinicalTrials.gov Identifier: NCT01389843.