Pattern searching/alignment with RNA primary and secondary structures: an effective descriptor for tRNA.

作者: Daniel Gautheret , Francois Major , Robert Cedergren

DOI: 10.1093/BIOINFORMATICS/6.4.325

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摘要: A convenient pattern-matching program using primary and higher-order structural features has been developed based on a 'backtracking' algorithm. second implementation of the algorithm uses descriptors (including sequences) to align list homologous or highly similar sequences. An application pattern matcher search for tRNA group I intron motifs in sequence data banks is presented. The design discriminate motif, common all cellular tRNAs not found control bank, was accomplished conjunction with alignment program.

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