Mindfulness-based stress reduction for Tourette syndrome and chronic tic disorder: A pilot study

摘要: Abstract Objective In this pilot study we sought to develop and test a modified form of mindfulness-based stress reduction (MBSR-tics) for the treatment Tourette Syndrome (TS) Chronic Tic Disorder (CTD). Our specific aims were: 1) To determine feasibility acceptability an 8-week trial MBSR-tics in individuals 16 older with TS or CTD 2) efficacy CTD. Methods Eighteen age 16–67 completed uncontrolled open MBSR-tics. The intervention consisted 8 weekly 2-hour classes one 4 hour retreat fifth sixth week program. Symptomatic assessments were performed at baseline, post-treatment, one-month follow-up. Results proved be feasible acceptable intervention. It resulted significant improvement tic severity tic-related impairment. 58.8% subjects deemed responders. Therapeutic gains maintained 1-month Improvements correlated increases self-reported levels mindfulness. Conclusions This small provides preliminary support feasibility, acceptability, A larger randomized controlled blind assessment is necessary confirm these initial, promising findings. Trial Registration Partners Clinical Trials Registry Number 2011P000606 (clinicaltrials.partners.org).