Anti-inflammatory principles from Cordyceps sinensis.
作者： Mei-Lin Yang , Ping-Chung Kuo , Tsong-Long Hwang , Tian-Shung Wu
DOI: 10.1021/NP100902F
关键词:
摘要: In order to explore the anti-inflammatory principles of mycelia Cordyceps sinensis, crude extract and partially purified fractions were examined for their inhibition superoxide anion generation elastase release. Further chemical investigation bioactive has resulted in identification 50 compounds, including five constituents, cordysinins A-E (1-5), reported from a natural source first time. addition, compounds activity. 1-(5-Hydroxymethyl-2-furyl)-β-carboline displayed most significant release with IC50 values 0.45±0.15 1.68±0.32 μM, respectively.
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