Antimicrobial investigation of Linum usitatissimum for the treatment of acne.

作者: Pratibha Nand Pratibha Nand , Sushma Drabu Sushma Drabu , RK Gupta

DOI: 10.1177/1934578X1100601133

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摘要: Light petroleum, dichloromethane and methanolic extracts of Linum usitatissimum were investigated using GC/MS. The main components three sequential methyl linolenate (11.9-33.9%) linoleate (3.4-9.1%). Components possessing antimicrobial activity against acne causing bacteria, namely alpha-linolenic acid (7.0 -7.1%), alpha-terpinene (1.7-3.1%), terpinen-4-ol (1.3-4.6%), 4-cymene (1.6-7.1%) alpha-pinene (1.1%), found in varying amounts. Antimicrobial screening indicated that the light petroleum extract was more active aerobic anaerobic test strains with a MIC value 1.25 mg/mL MBC 2.5 S. aureus P. acnes. A observed epidermidis.

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