Plasma homocysteine levels in patients with multiple sclerosis in the Greek population.

摘要: Abstract Background In recent years, there has been increasing interest in the role of plasma homocysteine (Hcy) as a possible risk factor for several diseases central nervous system. The aim this study was to determine levels Hcy group multiple sclerosis (MS) patients from Greek population and correlation with age, disability status, activity or duration disease, sex, treatment. Methods MS that studied consisted 46 total 42 healthy individuals served control group. Plasma were determined by means high-performance liquid chromatography coupled fluorescence detection, after precolumn derivatization 4-Fluoro-7-aminosulfonylbenzofurazan (ABD-F). Results Statistical analysis revealed that, patients, not significantly different compared those controls. Men presented higher than women group; however, disease subtype, duration, relapse rate, Expanded Disability Status Scale score/Multiple Sclerosis Severity Score did affect patients. Conclusion preliminary data suggest elevated our sample which does support previous findings significant between serum MS. Further studies establish association context ethnic groups habits are needed.