Transport of p-aminohippurate in renal cortical slices of rats of different ages following treatment with thyroid hormones.

摘要: Following treatment with thyroid hormones PAH accumulation is increased in renal cortical slices of 5-, 10-, 20-, 30-, 50- and 105-day-old rats. Both are more effective young than adult A single dose T3 or T4 (20 micrograms/100 g b.m.) administered 24 h before measurement whereas acute effects on transport could not be demonstrated. Treatment b.m., 3 days, once a day) without any influence body mass; there tendency to an increase kidney mass following T4. Simultaneous administration inhibitor protein biosynthesis (neomycin, 1 5 mg/100 reduces the effect treatment. An additional low T3, can restore which was performed 9 days before.