Predictors of lymph node metastases and impact on survival in resected pancreatic neuroendocrine tumors: a single-center experience.
作者： Joyce Wong , William J. Fulp , Jonathan R. Strosberg , Larry K. Kvols , Barbara A. Centeno
DOI: 10.1016/J.AMJSURG.2014.04.003
关键词:
摘要: Abstract Background Staging for pancreatic neuroendocrine tumors (PNET) considers tumor size and lymph node (LN) status; however, correlation with survival remains unclear. Methods A single-institution database of patients resected PNET was analyzed. Results Of the 150 patients, incidentally discovered most common presentation (42%). One hundred thirteen (75%) had LN data, 32 (28%) positive (LN+). Procedure did not predict LN+. Perineural invasion (P = .016) lymphovascular Conclusions has an unclear prognosis based on variables factored into stage. In this study, LN+; furthermore, LN+ impact overall or DFS. Tumor differentiation appears to be more important in determining prognosis.
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