Agmatine and agmatine analogs in the treatment of epilepsy, seizure, and electroconvulsive disorders
作者： Peter A. Crooks , David R. Worthen , Aimee K. Bence
DOI:
关键词:
摘要: Pharmaceutical preparations containing of agmatine, congeners, analogs or derivatives thereof for use in preventing treating epilepsy, seizures and other electroconvulsive disorders are provided. Embodiments include administering an effective amount agmatine analog a pharmaceutically acceptable salt to human subject need treatment prevention seizure disorder treat, reduce, prevent the subject.
lens.org 参考文章(30)
Brian Walter Metcalf, Michel Jung, α-ACETYLENIC DERIVATIVES OF AMINES ,(1977)
Dennis Bigg, Pierre-Etienne Chabrier de Lassauniere, Association of no syntase inhibitors with trappers of oxygen reactive forms ,(1997)
Michel Jung, Philippe Bey, .alpha.-HALOMETHYL DERIVATIVES OF AMINES ,(1978)
Gad M. Gilad, Varda H. Gilad, Agmatine for the treatment of neurotrauma and neurodegenerative diseases ,(1995)
D.J. Reis, S. Regunathan, AGMATINE : A NOVEL NEUROTRANSMITTER ? Advances in pharmacology. ,vol. 42, pp. 645- 649 ,(1997) , 10.1016/S1054-3589(08)60834-0
Magdalena SASTRE, Elena GALEA, Douglas FEINSTEIN, J. Donald REIS, Soundararajan REGUNATHAN, Metabolism of agmatine in macrophages: modulation by lipopolysaccharide and inhibitory cytokines. Biochemical Journal. ,vol. 330, pp. 1405- 1409 ,(1998) , 10.1042/BJ3301405
D J Reis, C Youngson, S Regunathan, H Wang, W Raasch, Imidazoline receptors and agmatine in blood vessels: a novel system inhibiting vascular smooth muscle proliferation. Journal of Pharmacology and Experimental Therapeutics. ,vol. 276, pp. 1272- 1282 ,(1996)
John Dorrance Minna, Fuh-Mei Duh, Ming-Hui Wei, Boning Gao, Michael Isaac Lerman, Farida Latif, Yoshitaka Sekido, Calcium channel compositions and methods of use thereof ,(1999)
George L. Wilcox, Tinna Marie Laughlin, Kristin Schreiber, Carolyn Ann Fairbanks, Agmatine as a treatment for neuropathic pain ,(1998)
İ.Tayfun Uzbay, Özgür Yeşilyurt, Turgay Çelik, Hakan Ergün, Aşkın Işımer, Effects of agmatine on ethanol withdrawal syndrome in rats Behavioural Brain Research. ,vol. 107, pp. 153- 159 ,(2000) , 10.1016/S0166-4328(99)00127-8