Sex differences in the control of glucose homeostasis.
作者： Ellen Blaak
DOI: 10.1097/MCO.0B013E32830467D3
关键词:
摘要: PURPOSE OF REVIEW: A markedly higher prevalence of impaired glucose tolerance has been reported in women than men whereas the opposite was seen for fasting glucose. The present review focuses on underlying mechanisms. RECENT FINDINGS: An increased meal appearance and disturbances postprandial disposal may contribute to concentrations women. similar or reduced insulin sensitivity which makes it unclear what extent a disturbed insulin-mediated This discrepancy be explained by differences phase menstrual cycle during study use oral contraceptives different degrees physical fitness. Nevertheless there are consistent data indicating that protected against fatty acid-induced resistance. Furthermore both endogenous output metabolic clearance SUMMARY: There is an urgent need studies test whether sex-related metabolism involved pathogenesis type 2 diabetes syndrome taking age activity into account.
narcis.nl参考文章(27)
A C Hackney, M Wenz, N A Lynch, S Chappell, J Z Berend, Substrate oxidation at rest and during exercise: effects of menstrual cycle phase and diet composition Journal of Physiology and Pharmacology. ,vol. 48, pp. 851- 860 ,(1997)
A-M. Borissova, T. Tankova, G. Kirilov, D. Koev, Gender-dependent effect of ageing on peripheral insulin action. International Journal of Clinical Practice. ,vol. 59, pp. 422- 426 ,(2005) , 10.1111/J.1368-5031.2005.00209.X
J. Pomerleau, P. M. McKeigue, N. Chaturvedi, Relationships of fasting and postload glucose levels to sex and alcohol consumption - Are American Diabetes Association criteria biased against detection of diabetes in women? Diabetes Care. ,vol. 22, pp. 430- 433 ,(1999) , 10.2337/DIACARE.22.3.430
L. Hellström, E. Blaak, E. Hagström-Toft, Gender differences in adrenergic regulation of lipid mobilization during exercise. International Journal of Sports Medicine. ,vol. 17, pp. 439- 447 ,(1996) , 10.1055/S-2007-972875
J. W. Williams, P. Z. Zimmet, J. E. Shaw, M. P. de Courten, A. J. Cameron, P. Chitson, J. Tuomilehto, K. G. M. M. Alberti, Gender differences in the prevalence of impaired fasting glycaemia and impaired glucose tolerance in Mauritius. Does sex matter Diabetic Medicine. ,vol. 20, pp. 915- 920 ,(2003) , 10.1046/J.1464-5491.2003.01059.X
Maarten R Soeters, Hans P Sauerwein, Johanna E Groener, Johannes M Aerts, Mariëtte T Ackermans, Jan FC Glatz, Eric Fliers, Mireille J Serlie, None, Gender-Related Differences in the Metabolic Response to Fasting The Journal of Clinical Endocrinology and Metabolism. ,vol. 92, pp. 3646- 3652 ,(2007) , 10.1210/JC.2007-0552
Yoshihisa Nemoto, Katsumi Toda, Masafumi Ono, Kiyomi Fujikawa-Adachi, Toshiji Saibara, Saburo Onishi, Hideaki Enzan, Teruhiko Okada, Yutaka Shizuta, Altered expression of fatty acid–metabolizing enzymes in aromatase-deficient mice Journal of Clinical Investigation. ,vol. 105, pp. 1819- 1825 ,(2000) , 10.1172/JCI9575
Ellen Blaak, Gender differences in fat metabolism. Current Opinion in Clinical Nutrition and Metabolic Care. ,vol. 4, pp. 499- 502 ,(2001) , 10.1097/00075197-200111000-00006
G.P. Carnevale Schianca, L. Castello, R. Rapetti, A. Limoncini, E. Bartoli, Insulin sensitivity: Gender-related differences in subjects with normal glucose tolerance Nutrition Metabolism and Cardiovascular Diseases. ,vol. 16, pp. 339- 344 ,(2006) , 10.1016/J.NUMECD.2005.05.004
Per Björntorp, Body fat distribution, insulin resistance, and metabolic diseases Nutrition. ,vol. 13, pp. 795- 803 ,(1997) , 10.1016/S0899-9007(97)00191-3