Circulating Corticosterone Reaction to Restraint and Adrenocorticotropin Hormone Administration in White Leghorns Selected for Immune Response Traits

作者: G. Minozzi , D. Guéméné , M. Couty , D. Gourichon , F. Minvielle

DOI: 10.3382/PS.2008-00199

关键词:

摘要: Abstract Corticosterone plasma concentration was measured in a random-bred control line and 3 White Leghorn chicken lines previously selected over 9 generations for different vivo immune responses: high antibody response to Newcastle disease virus vaccine wk after vaccination (ND3), cell-mediated (response phytohemagglutinin, PHA), phagocytic activity as carbon clearance (CC). The objective of the study estimate if selection on had an effect stress assessed by measures corticosterone before physical or adrenocorticotropin hormone injection dependent trait that been for, joint analyses responses concentrations. mean values did not differ between lines, indicating little stress. Within line, however, significant negative correlations (−0.46 ≤ r −0.39) were found immunity concentrations 4 lines. Moreover, titers (ND3-L), levels positively correlated ND3 (r = 0.41 0.47) negatively CC −0.48).

参考文章(21)
J. Odihambo Mumma, J.P. Thaxton, Y. Vizzier-Thaxton, W.L. Dodson, Physiological Stress in Laying Hens Poultry Science. ,vol. 85, pp. 761- 769 ,(2006) , 10.1093/PS/85.4.761
WK Al-Murrani, AJ Al-Rawi, MF Al-Hadithi, B Al-Tikriti, None, Association between heterophil/lymphocyte ratio, a marker of 'resistance' to stress, and some production and fitness traits in chickens. British Poultry Science. ,vol. 47, pp. 443- 448 ,(2006) , 10.1080/00071660600829118
Robert J. Handa, Loyd H. Burgess, Janice E. Kerr, Joan A. O'Keefe, Gonadal Steroid Hormone Receptors and Sex Differences in the Hypothalamo-Pituitary-Adrenal Axis Hormones and Behavior. ,vol. 28, pp. 464- 476 ,(1994) , 10.1006/HBEH.1994.1044
P. Thaxton, H.S. Siegel, Modification of High Temperature and ACTH Induced Immunodepression by Metyrapone Poultry Science. ,vol. 52, pp. 618- 624 ,(1973) , 10.3382/PS.0520618
L. Star, M.G.B. Nieuwland, B. Kemp, H.K. Parmentier, Effect of Single or Combined Climatic and Hygienic Stress on Natural and Specific Humoral Immune Competence in Four Layer Lines Poultry Science. ,vol. 86, pp. 1894- 1903 ,(2007) , 10.1093/PS/86.9.1894
Giulietta Minozzi, Henk K Parmentier, Sandrine Mignon-Grasteau, Mike GB Nieuwland, Bertrand Bed'hom, David Gourichon, Francis Minvielle, Marie-Helen Pinard-van der Laan, Correlated effects of selection for immunity in White Leghorn chicken lines on natural antibodies and specific antibody responses to KLH and M. butyricum. BMC Genetics. ,vol. 9, pp. 5- 5 ,(2008) , 10.1186/1471-2156-9-5
Jeanette I. Webster Marketon, Ronald Glaser, Stress hormones and immune function Cellular Immunology. ,vol. 252, pp. 16- 26 ,(2008) , 10.1016/J.CELLIMM.2007.09.006