Comparison of calcitonin versus calcitonin + resistance exercise as prophylaxis for osteoporosis in heart transplant recipients.
作者： Randy W. Braith , Peter M. Magyari , Michael N. Fulton , Clem F. Lisor , Sara E. Vogel
DOI: 10.1097/01.TP.0000176927.43937.BB
关键词:
摘要: BACKGROUND Rapid bone loss occurs early after heart transplantation. There is no standard therapeutic intervention to prevent osteoporosis in transplant recipients (HTR). The purpose of this study was determine the effectiveness a regimen combining antiresorptive properties nasal calcitonin with osteogenic stimulus resistance exercise. METHODS Eighteen candidates for transplantation were randomly assigned either group that received and participated 6 months exercise (n=10) or only (n=8). Calcitonin therapy (200 IU daily 8 months) initiated 48 hr Resistance 2 Bone mineral density (BMD) total body, femur neck, lumbar vertebra (L2-3) assessed before, at RESULTS Total body neck BMD did not decrease (P>or=0.05) below pretransplantation values group. spine significantly (P
sci-hub.se 参考文章(15)
JAMES E. GRAVES, MICHAEL L. POLLOCK, DAN FOSTER, SCOTT H. LEGGETT, DAVID M. CARPENTER, ROSEMARIA VUOSO, ARTHUR JONES, Effect of training frequency and specificity on isometric lumbar extension strength. Spine. ,vol. 15, pp. 504- 509 ,(1990) , 10.1097/00007632-199006000-00014
Robert Lindsay, Bone loss after cardiac transplantation. The New England Journal of Medicine. ,vol. 350, pp. 751- 754 ,(2004) , 10.1056/NEJMP038240
Randy W. Braith, Roger M. Mills, Michael A. Welsch, Jeffrey W. Keller, Michael L. Pollock, Resistance exercise training restores bone mineral density in heart transplant recipients Journal of the American College of Cardiology. ,vol. 28, pp. 1471- 1477 ,(1996) , 10.1016/S0735-1097(96)00347-6
RANDY W. BRAITH, MICHAEL A. WELSCH, ROGER M. MILLS, JEFFREY W. KELLER, MICHAEL L. POLLOCK, Resistance exercise prevents glucocorticoid-induced myopathy in heart transplant recipients Medicine and Science in Sports and Exercise. ,vol. 30, pp. 483- 489 ,(1998) , 10.1097/00005768-199804000-00003
Matthew J. Mitchell, Maher A. Baz, Michael N. Fulton, Clem F. Lisor, Randy W. Braith, Resistance training prevents vertebral osteoporosis in lung transplant recipients. Transplantation. ,vol. 76, pp. 557- 562 ,(2003) , 10.1097/01.TP.0000076471.25132.52
Elizabeth Shane, Maria Del C Rivas, Shonni J Silverberg, Tae Sook Kim, Ronald B Staron, John P Bilezikian, None, Osteoporosis after cardiac transplantation The American Journal of Medicine. ,vol. 94, pp. 257- 264 ,(1993) , 10.1016/0002-9343(93)90057-V
D. Carpenter, J. Tucci, M. Pollock, J. Graves, D. Feurtado, R. Mananquil, Effect Of Repositioning On Intraday Reliability Of Lateral Lumbar Spine Bone Measurements Using Dual Energy X-ray Absorptiometry: 389 Medicine and Science in Sports and Exercise. ,vol. 24, ,(1992) , 10.1249/00005768-199205001-00390
Randy W Braith, Peter M Magyari, Michael N Fulton, Juan Aranda, Tracy Walker, James A Hill, Resistance exercise training and alendronate reverse Glucocorticoid-Induced osteoporosis in heart transplant recipients Journal of Heart and Lung Transplantation. ,vol. 22, pp. 1082- 1090 ,(2003) , 10.1016/S1053-2498(02)01184-1
S. Epstein, I.R. Dissanayake, G.R. Goodman, A.R. Bowman, H. Zhou, Y. Ma, W.S.S. Jee, Effect of the Interaction of Parathyroid Hormone and Cyclosporine A on Bone Mineral Metabolism in the Rat Calcified Tissue International. ,vol. 68, pp. 240- 247 ,(2001) , 10.1007/S002230001167
Adi Cohen, Elizabeth Shane, None, Osteoporosis after solid organ and bone marrow transplantation. Osteoporosis International. ,vol. 14, pp. 617- 630 ,(2003) , 10.1007/S00198-003-1426-Z