The hidden harm behind the return of results from personal genome services: a need for rigorous and responsible evaluation.
作者： A. Cecile J.W. Janssens
DOI: 10.1038/GIM.2014.169
关键词:
摘要: The hidden harm behind the return of results from personal genome services: a need for rigorous and responsible evaluation
nature.com
narcis.nl参考文章(13)
Theresa M Marteau, David P French, Simon J Griffin, A T Prevost, Stephen Sutton, Clare Watkinson, Sophie Attwood, Gareth J Hollands, Effects of communicating DNA‐based disease risk estimates on risk‐reducing behaviours Cochrane Database of Systematic Reviews. ,(2010) , 10.1002/14651858.CD007275.PUB2
Robert C. Green, J. Scott Roberts, L. Adrienne Cupples, Norman R. Relkin, Peter J. Whitehouse, Tamsen Brown, Susan LaRusse Eckert, Melissa Butson, A. Dessa Sadovnick, Kimberly A. Quaid, Clara Chen, Robert Cook-Deegan, Lindsay A. Farrer, Disclosure of APOE Genotype for Risk of Alzheimer's Disease The New England Journal of Medicine. ,vol. 361, pp. 245- 254 ,(2009) , 10.1056/NEJMOA0809578
Sarah M. Hartz, Emily Olfson, Robert Culverhouse, Patricia Cavazos-Rehg, Li-Shiun Chen, James DuBois, Sherri Fisher, Kimberly Kaphingst, David Kaufman, Andrew Plunk, Shelina Ramnarine, Stephanie Solomon, Nancy L. Saccone, Laura J. Bierut, Return of individual genetic results in a high-risk sample: enthusiasm and positive behavioral change. Genetics in Medicine. ,vol. 17, pp. 374- 379 ,(2015) , 10.1038/GIM.2014.110
Rachel R.J. Kalf, Raluca Mihaescu, Suman Kundu, Peter de Knijff, Robert C. Green, A. Cecile J.W. Janssens, Variations in predicted risks in personal genome testing for common complex diseases Genetics in Medicine. ,vol. 16, pp. 85- 91 ,(2014) , 10.1038/GIM.2013.80
Robert C Green, Nita A Farahany, Regulation: The FDA is overcautious on consumer genomics Nature. ,vol. 505, pp. 286- 287 ,(2014) , 10.1038/505286A
Kimberly A. Kaphingst, Colleen M. McBride, Christopher Wade, Sharon Hensley Alford, Robert Reid, Eric Larson, Andreas D. Baxevanis, Lawrence C. Brody, Patients' understanding of and responses to multiplex genetic susceptibility test results. Genetics in Medicine. ,vol. 14, pp. 681- 687 ,(2012) , 10.1038/GIM.2012.22
Uta Francke, Cheri Dijamco, Amy K. Kiefer, Nicholas Eriksson, Bianca Moiseff, Joyce Y. Tung, Joanna L. Mountain, Dealing with the unexpected: consumer responses to direct-access BRCA mutation testing PeerJ. ,vol. 1, ,(2013) , 10.7717/PEERJ.8
Jose M de Miguel-Yanes, Peter Shrader, Michael J Pencina, Caroline S Fox, Alisa K Manning, Richard W Grant, Josèe Dupuis, Jose C Florez, Ralph B D'Agostino Sr, L Adrienne Cupples, James B Meigs, MAGIC Investigators, DIAGRAM+ Investigators, None, Genetic risk reclassification for type 2 diabetes by age below or above 50 years using 40 type 2 diabetes risk single nucleotide polymorphisms. Diabetes Care. ,vol. 34, pp. 121- 125 ,(2011) , 10.2337/DC10-1265
Linnea M Baudhuin, The FDA and 23andMe: Violating the First Amendment or Protecting the Rights of Consumers? Clinical Chemistry. ,vol. 60, pp. 835- 837 ,(2014) , 10.1373/CLINCHEM.2014.223321
Cinnamon S Bloss, Nathan E Wineinger, Burcu F Darst, Nicholas J Schork, Eric J Topol, Impact of direct-to-consumer genomic testing at long term follow-up Journal of Medical Genetics. ,vol. 50, pp. 393- 400 ,(2013) , 10.1136/JMEDGENET-2012-101207