The SWISS-PROT protein knowledgebase and its supplement TrEMBL in 2003

摘要: The SWISS-PROT protein knowledgebase (http://www.expasy.org/sprot/ and http://www.ebi.ac.uk/swissprot/) connects amino acid sequences with the current knowledge in Life Sciences. Each entry provides an interdisciplinary overview of relevant information by bringing together experimental results, computed features sometimes even contradictory conclusions. Detailed expertise that goes beyond scope is made available via direct links to specialised databases. annotated entries for all species, but concentrates on annotation from human (the HPI project) other model organisms ensure presence high quality representative members families. Part can be transferred family members, as already done microbes High-quality Automated Manual Annotation microbial Proteomes (HAMAP) project. Protein families groups proteins are regularly reviewed keep up scientific findings. Complementarily, TrEMBL strives comprise not yet represented SWISS-PROT, incorporating a perpetually increasing level mostly automated annotation. Researchers welcome contribute their community submitting findings at swiss-prot@expasy.org.