Endoplasmic reticulum stress and eIF2α phosphorylation: The Achilles heel of pancreatic β cells

作者: Miriam Cnop , Sanna Toivonen , Mariana Igoillo-Esteve , Paraskevi Salpea

DOI: 10.1016/J.MOLMET.2017.06.001

关键词:

摘要: … our understanding of pathogenic mechanisms. Finally, we … This dominant C96Y INS mutation causes ER stress by the … and downstream signaling are enhanced. Loss-of-function …

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