摘要: Streptococcus mutans is considered one of the primary causative agents dental caries and can also be a source infective endocarditis. The main virulence factors associated with cariogenicity include adhesion, acidogenicity, acid tolerance. Each these properties works coordinately to alter plaque ecology. ecological changes are characterized by increased proportions S. other species that similarly acidogenic aciduric. selection for cariogenic flora increases magnitude drop in pH following fermentation available carbohydrate probability enamel demineralization. This review focuses on bacterial components contribute each major properties. Further understanding how work together development will aided recent completion sequence genome experimental designs model biofilm.