Survival changes in patients with small cell lung cancer and disparities between different sexes, socioeconomic statuses and ages
作者： Shuncong Wang , Jianjun Tang , Tiantian Sun , Xiaobin Zheng , Jie Li
DOI: 10.1038/S41598-017-01571-0
关键词:
摘要: Small cell lung cancer (SCLC), as a proportion, makes up only 15–17% of cases. The development treatments for SCLC has remained stagnant decades, and is expected to persist threat human health. To date, no publications based on large populations have been reported. We calculated survival changes in patients with during each decade between 1983 2012 determine the roles race, sex, age, socioeconomic status (SES) rates Surveillance, Epidemiology, End Results (SEER) registries. In total, 106,296 were identified, overall incidence per 100,000 decreasing from 9.6 7.8 5.8. median 7 months, 12-month relative (RSRs) relatively stable at 32.9%, 33.2% decade. 5-year RSRs significantly improved 4.9% 5.9% 6.4% decade, but extremely low. addition, narrowing gaps among SES groups sexes observed. Although decreased stable, highlighting urgency developing novel importance prevention early detection.
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Kenneth A. Perkins, Smoking cessation in women. Special considerations. CNS Drugs. ,vol. 15, pp. 391- 411 ,(2001) , 10.2165/00023210-200115050-00005
Thomas Hensing, Apoorva Chawla, Rishi Batra, Ravi Salgia, A Personalized Treatment for Lung Cancer: Molecular Pathways, Targeted Therapies, and Genomic Characterization Advances in Experimental Medicine and Biology. ,vol. 799, pp. 85- 117 ,(2014) , 10.1007/978-1-4614-8778-4_5
Igor Sitartchouk, Hamid Bayanati, Frances A Shepherd, Demetris Patsios, Gordon Weisbrod, Thomas Waddell, Taebong Chung, Narinder S Paul, Andre Pereira, Gail Darling, Steven Herman, Heidi C Roberts, Shafique Keshavjee, Maureen McGregor, Ming Tsao, Scott Boerner, Ashwini Kale, Lung cancer screening with low-dose computed tomography: Canadian experience. Canadian Association of Radiologists journal. ,vol. 58, pp. 225- 235 ,(2007)
Pramit Nadpara, S. Suresh Madhavan, Cindy Tworek, Guideline-concordant timely lung cancer care and prognosis among elderly patients in the United States: A population-based study. Cancer Epidemiology. ,vol. 39, pp. 1136- 1144 ,(2015) , 10.1016/J.CANEP.2015.06.005
Anish Thomas, Stephen V. Liu, Deepa S. Subramaniam, Giuseppe Giaccone, Refining the treatment of NSCLC according to histological and molecular subtypes Nature Reviews Clinical Oncology. ,vol. 12, pp. 511- 526 ,(2015) , 10.1038/NRCLINONC.2015.90
Bree R. Eaton, Sungjin Kim, David M. Marcus, Roshan Prabhu, Zhengjia Chen, Suresh S. Ramalingam, Walter J. Curran, Kristin A. Higgins, Effect of prophylactic cranial irradiation on survival in elderly patients with limited-stage small cell lung cancer. Cancer. ,vol. 119, pp. 3753- 3760 ,(2013) , 10.1002/CNCR.28267
Shadia I. Jalal, Raghava Induru, Hirva Mamdani, Novel therapies in small cell lung cancer Translational lung cancer research. ,vol. 4, pp. 533- 544 ,(2015) , 10.3978/J.ISSN.2218-6751.2015.07.20
John P. Chute, Timothy Chen, Ellen Feigal, Richard Simon, Bruce E. Johnson, Twenty Years of Phase III Trials for Patients With Extensive-Stage Small-Cell Lung Cancer: Perceptible Progress Journal of Clinical Oncology. ,vol. 17, pp. 1794- 1794 ,(1999) , 10.1200/JCO.1999.17.6.1794
Julie George, Jing Shan Lim, Se Jin Jang, Yupeng Cun, Luka Ozretić, Gu Kong, Frauke Leenders, Xin Lu, Lynnette Fernández-Cuesta, Graziella Bosco, Christian Müller, Ilona Dahmen, Nadine S Jahchan, Kwon-Sik Park, Dian Yang, Anthony N Karnezis, Dedeepya Vaka, Angela Torres, Maia Segura Wang, Jan O Korbel, Roopika Menon, Sung-Min Chun, Deokhoon Kim, Matt Wilkerson, Neil Hayes, David Engelmann, Brigitte Pützer, Marc Bos, Sebastian Michels, Ignacija Vlasic, Danila Seidel, Berit Pinther, Philipp Schaub, Christian Becker, Janine Altmüller, Jun Yokota, Takashi Kohno, Reika Iwakawa, Koji Tsuta, Masayuki Noguchi, Thomas Muley, Hans Hoffmann, Philipp A Schnabel, Iver Petersen, Yuan Chen, Alex Soltermann, Verena Tischler, Chang-min Choi, Yong-Hee Kim, Pierre P Massion, Yong Zou, Dragana Jovanovic, Milica Kontic, Gavin M Wright, Prudence A Russell, Benjamin Solomon, Ina Koch, Michael Lindner, Lucia A Muscarella, Annamaria La Torre, John K Field, Marko Jakopovic, Jelena Knezevic, Esmeralda Castaños-Vélez, Luca Roz, Ugo Pastorino, Odd-Terje Brustugun, Marius Lund-Iversen, Erik Thunnissen, Jens Köhler, Martin Schuler, Johan Botling, Martin Sandelin, Montserrat Sanchez-Cespedes, Helga B Salvesen, Viktor Achter, Ulrich Lang, Magdalena Bogus, Peter M Schneider, Thomas Zander, Sascha Ansén, Michael Hallek, Jürgen Wolf, Martin Vingron, Yasushi Yatabe, William D Travis, Peter Nürnberg, Christian Reinhardt, Sven Perner, Lukas Heukamp, Reinhard Büttner, Stefan A Haas, Elisabeth Brambilla, Martin Peifer, Julien Sage, Roman K Thomas, None, Comprehensive genomic profiles of small cell lung cancer Nature. ,vol. 524, pp. 47- 53 ,(2015) , 10.1038/NATURE14664
Gerhard Hamilton, Barbara Rath, Smoking, inflammation and small cell lung cancer: recent developments Wiener Medizinische Wochenschrift. ,vol. 165, pp. 379- 386 ,(2015) , 10.1007/S10354-015-0381-6