Human T-Lymphotropic Virus Type 2 (HTLV-2) Provirus in Circulating Cells of the Monocyte/Macrophage Lineage in Patients Dually Infected with Human Immunodeficiency Virus Type 1 and HTLV-2 and Having Predominantly Sensory Polyneuropathy

作者: Gianguglielmo Zehender , Luca Meroni , Stefania Varchetta , Chiara De Maddalena , Barbara Cavalli

DOI: 10.1128/JVI.72.9.7664-7668.1998

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摘要: We investigated the presence of human T-lymphotropic virus type 2 (HTLV-2) DNA in peripheral blood mononuclear cell subsets obtained from 18 patients coinfected with immunodeficiency 1 and HTLV-2, 6 whom also had predominantly sensory polyneuropathy (PSP). HTLV-2 RNA were found CD8- CD19-positive cells, and, for PSP, CD14-positive cells as well. Furthermore, PSP higher proviral loads than those without PSP.

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