Total parenteral nutrition in familial hypercholesterolemia: importance of caloric control.

摘要: Effects of total parenteral nutrition (TPN) on serum cholesterol levels were examined in four patients with homozygous and three heterozygous familial hypercholesterolemia 13 without hypercholesterolemia. Fat-free TPN was administered average doses 26.5 cal/kg/day (43.6 a child) for 5 to 14 weeks. The level decreased markedly by 47.5% 58.6% cases, respectively. Despite restriction calories TPN, protein maintained all patients. It became apparent that hypercholesterolemia, whether the or form, performed at well-adjusted caloric intake provided an adequate control as far continued. In under varied correlatively amount be administered. Compared values before fourth week elevated receiving more than 40 cal/kg/day, while it reduced given less cal/kg/day. There statistically significant correlation between daily per body weight change TPN. This indicates is importance TPN-induced levels.