Histocompatibility of Acellular Matrix Bone with Osteoblast and Vascular Endothelial Cells

摘要: The culture of stem cells is an essential element in tissue engineering.The base for the repairing bone defect engineering still its vascularization. Co-culture osteoblast and vascular endothelial cell (VEC) can not only promote proliferative activity but also accelerate revascularization regenerating bone. Thus it help to increase ability defect. source site supplying were limited autografting, meanwhile difficult modeling self-tissue, therefore clinical application limited. There certain immunologic rejection isotype heterogenous grafting provides a new way solving this problem. In experiment, compounded by using acellular rib pig. Then was constructed implanted into animal. Observe study biological compatibility, try find out pathological process vivo ossification, revascularizarion grafting. will provide theological This chapter divided 3 parts: Part I: seed cellular II: Study effect matrix (HBACM) on compatibility between osteoblasts cells, III experimental research implanting compound animal body.