Adeno-associated virus (AAV) as a vector for gene transfer into glial cells of the human central nervous system.

摘要: To examine the potential of AAV as a vector for gene transfer in glial cells, an established astrocytoma cell line and short-term cultures derived from human oligodendroglioma have been coinfected with helper adenovirus. The level replication glioma cells was high indicating that they express receptors AAV.