Pathophysiology, Diagnosis, and Management of Infections in Atopic Dermatitis

摘要: Atopic dermatitis (AD) is a common and chronic inflammatory skin disease. The purpose of this review article to assess recent changes in the understanding pathophysiology, diagnosis, management infections AD. Recent epidemiological studies have confirmed that AD not only associated with cutaneous infections, but also extra-cutaneous systemic infections. Basic provided evidence allergic inflammation contribute increased Clinical use diluted bleach prevent remains controversial. On other hand, progress being made study microbiome Commensal bacteria may potentially be used fight Staphylococcus aureus future. complex disease arising from barrier defects lead allergen or pathogen invasion dysfunctional immune responses promote inflammation. This cycle alters so pathogenic organisms, such as S. aureus, are more likely colonize skin. defects, dysregulation, alteration an risk for secondary bacterial viral More targeted therapies probiotics address prevention