Multimodality imaging in macular telangiectasia 2: A clue to its pathogenesis.

摘要: Macular telangiectasia type 2 also known as idiopathic perifoveal and juxtafoveolar retinal telangiectasis 2A is an acquired bilateral neurodegenerative macular disease that manifests itself during the fifth or sixth decades of life. It characterized by minimal dilatation parafoveal capillaries with graying area involved, a lack lipid exudation, right-angled venules, refractile deposits in superficial retina, hyperplasia pigment epithelium, foveal atrophy, subretinal neovascularization (SRNV). Our understanding has paralleled advances multimodality imaging fundus. Optical coherence tomography (OCT) images typically demonstrate presence intraretinal hyporeflective spaces are usually not related to thickening fluorescein leakage. The typical angiographic (FA) finding deep hyperfluorescent staining temporal area. With time, may involve whole but does extend center fovea. Long-term prognosis for central vision poor, because development SRNV atrophy. Its pathogenesis remains unclear FA, spectral domain OCT, adaptive optics, confocal blue reflectance short wave fundus autofluorescence implicate Muller cells pigment. Currently, there no treatment this condition.