Metabolic abnormalities in patients with inflammatory rheumatic diseases

摘要: Patients with rheumatoid arthritis (RA) experience an increased cardiometabolic risk factor burden that is substantially driven by systemic inflammation. This occurs less consistently in patients ankylosing spondylitis (AS). Psoriatic most strongly associates excess adiposity and metabolic risk. RA also often have inflammation-induced proinflammatory high-density lipoprotein (HDL) cholesterol particles lean/muscle mass loss association adiposity, a condition termed cachexia, which further enhances cardiovascular The presence of HDL lean was reported AS. Individualized aerobic resistance exercise programs can improve body composition profiles Future studies should assess how long-term lifestyle changes be effectuated if these influence events inflammatory rheumatic diseases. Herein, we review the current evidence on abnormalities arthritis. We propose management strategies research agenda.