Social behavioral correlates of Kaposi sarcoma-associated herpesvirus infection among Han and Uygur populations in Xinjiang, China.

摘要: BACKGROUND Kaposi sarcoma-associated herpesvirus (KSHV) is endemic in Xinjiang, China and its prevalence varies considerably across ethnic groups. The current study explored the correlates of KSHV infection among Han Uygur populations Xinjiang. METHODS A cross-sectional study, including 282 ethnicity 312 Uygur, was conducted China. All participants underwent face to questionnaire interview. Plasma samples were collected screened for using immunofluorescence assay. Univariate multivariate analyses examine seropositivity. RESULTS seroprevalence 41.6% (95% confidence interval [CI], 37.6-45.6) overall higher group (59.9%; 95% CI, 54.3-65.4) than (21.3%; 16.6-26.5). significant difference geometric mean titer (GMT) antibodies detected between groups (158.2; interquartile range [IQR], 80-320 vs 89.1; IQR, 40-160; P < 0.001). After adjusting potential confounders, (odds ratios [OR], 5.96; 4.05-8.90), age greater or equal 50 years (OR, 1.84; 1.24-2.77), preference meat diet 2.15; 1.05-4.46) significantly associated with increased odds CONCLUSION demonstrated high both There an urgent need programmatic adaptation address primary prevention interventions this region.