The Effect of Grape Seed Extract Supplementation on Performance, Antioxidant Enzyme Activity, and Immune Responses in Broiler Chickens Exposed to Chronic Heat Stress

摘要: The effect of grape seed extract (GSE) feed supplementation on performance, antioxidant enzyme activity, and immune responses in broiler chickens suffering from heat stress were investigated this study. Experimental diets including control diet (with no additive), 3 levels GSE (150, 300, 450 mg/kg), one level vitamin C (300 mg/kg) as a positive fed to the birds 1 42 d age. chronic (34±1 ˚C temperature for 5 hours per day) was provided 29 up 300 mg/kg increased average daily gain compared group prior (1-28 d). During condition, dietary at rate improved conversion ratio. IgG titer primary secondary response sheep red blood cell (SRBC) injection. In addition, with diet), or diet) had higher titers SRBC. reduced heterophil percent, heterophil/lymphocyte ratio, percentage lymphocyte broilers under stress. Supplementation (300, glutathione peroxidase (GPx) activity condition. did not affect results cutaneous basophil hypersensitivity (CBH) response, relative weights spleen bursa fabricius However, weight thymus Thus, could alleviate detrimental effects better than it is preferable health economic goals since natural waste by-product.