Nanogel Tectonics for Tissue Engineering: Protein Delivery Systems with Nanogel Chaperones

作者: Yoshihide Hashimoto , Sada‐atsu Mukai , Yoshihiro Sasaki , Kazunari Akiyoshi

DOI: 10.1002/ADHM.201800729

关键词:

摘要: Amphiphilic polysaccharide self-assembled (SA) nanogels are promising protein carriers owing to their chaperone-like activity that allows them nanoencapsulate proteins within polymer networks. The chaperoning function is an important concept has led breakthroughs in the development of effective drug delivery systems by stabilizing formulations and controlling quality unstable proteins. Recently, nanogel-tectonic materials integrate SA as building blocks have been designed new hydrogel biomaterials. This article describes recent progress applications nanogel tectonic for tissue engineering.

参考文章(130)
DF Bowen-Pope, TW Malpass, DM Foster, R Ross, Platelet-derived growth factor in vivo: levels, activity, and rate of clearance Blood. ,vol. 64, pp. 458- 469 ,(1984) , 10.1182/BLOOD.V64.2.458.BLOODJOURNAL642458
Junzo Sunamoto, Hiroki Fukui, Kazunari Akiyoshi, Ikuo Taniguchi, Hydrogel nanoparticle formed by self-assembly of hydrophobized polysaccharide. Stabilization of adriamycin by complexation European Journal of Pharmaceutics and Biopharmaceutics. ,vol. 42, pp. 286- 290 ,(1996)
Nirat Beohar, Jonathan Rapp, Sanjay Pandya, Douglas W. Losordo, Rebuilding the Damaged Heart : The Potential of Cytokines and Growth Factors in the Treatment of Ischemic Heart Disease Journal of the American College of Cardiology. ,vol. 56, pp. 1287- 1297 ,(2010) , 10.1016/J.JACC.2010.05.039
Yoshihiro Sasaki, Kazunari Akiyoshi, Nanogel Engineering by Associating Polymers for Biomedical Applications Wiley‐VCH Verlag GmbH & Co. KGaA. pp. 187- 208 ,(2012) , 10.1002/9783527646425.CH8
Kazuhiro Aoki, Toshimi Sato, Neil Alles, Masud Khan, Kenichi Nagano, Mariko Takahashi, Yukihiko Tamura, Asako Shimoda, Kazunari Akiyoshi, Keiichi Ohya, Nanogel-crosslinked nanoparticles increase the inhibitory effects of W9 synthetic peptide on bone loss in a murine bone resorption model. International Journal of Nanomedicine. ,vol. 10, pp. 3459- 3473 ,(2015) , 10.2147/IJN.S61566
A. Stavropoulos, U. M. E. Wikesjö, Growth and differentiation factors for periodontal regeneration: a review on factors with clinical testing. Journal of Periodontal Research. ,vol. 47, pp. 545- 553 ,(2012) , 10.1111/J.1600-0765.2012.01478.X
Yoshiro Tahara, Kazunari Akiyoshi, Current advances in self-assembled nanogel delivery systems for immunotherapy Advanced Drug Delivery Reviews. ,vol. 95, pp. 65- 76 ,(2015) , 10.1016/J.ADDR.2015.10.004
Takayuki Miyahara, Myat Nyan, Asako Shimoda, Yuka Yamamoto, Shinji Kuroda, Makoto Shiota, Kazunari Akiyoshi, Shohei Kasugai, Exploitation of a novel polysaccharide nanogel cross-linking membrane for guided bone regeneration (GBR) Journal of Tissue Engineering and Regenerative Medicine. ,vol. 6, pp. 666- 672 ,(2012) , 10.1002/TERM.475
K. Akiyoshi, J. Sunamoto, Supramolecular assembly of hydrophobized polysaccharides Supramolecular Science. ,vol. 3, pp. 157- 163 ,(1996) , 10.1016/0968-5677(96)00031-4
Sayaka Toita, Shin-ichi Sawada, Kazunari Akiyoshi, Polysaccharide nanogel gene delivery system with endosome-escaping function: Co-delivery of plasmid DNA and phospholipase A2. Journal of Controlled Release. ,vol. 155, pp. 54- 59 ,(2011) , 10.1016/J.JCONREL.2010.12.008