Health-related quality of life and disease severity of SLE patients in Phramongkutklao Hospital.

作者: Sumapa Chaiamnuay , Pongthorn Narongroeknawin , Paijit Asavatanabodee , Suphawan Phukongchai , Viyanuch Lomaratana

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摘要: Background: The studies of association disease activity and damage with health-related quality life (HRQOL) in lupus have shown equivocal results has not been studied Thailand. Objective: To examine the HRQOL to between SLE severity (disease damage) Thai patients. Material Method: Short Form-36 (SF-36) was applied 95 consecutive At time assessment, all patients were evaluated for [disease as measured by Mexican Systemic Lupus Erythematosus Disease Activity Index (Mex-SLEDAI) International Collaborating Clinic/American College Rheumatology (SLICC/ACR) index (SDI)]. physical (PCS) mental component summary (MCS) SF-36 examined Pearson’s correlation. Results: Ninety-five (93 females 2 males) included (mean age 39.84 + 10.91). mean duration 115 83 months. scores MCS PCS 45.5 9.5 41.1 9.3, respectively. higher SDI correlated lower but (PCS, r = -0.411, p < 0.001). There no correlation (both PCS) activity. Conclusion: inversely Keywords: erythematosus, Health related life, activity, Damage,

参考文章(24)
P. Stratta, P. Mesiano, A. Campo, A. Grill, S. Ferrero, S. Santi, L. Besso, G. Mazzucco, S. Rosso, A. Spitale, F. Fop, G. Ciccone, Life expectancy of women with lupus nephritis now approaches that of the general population. International Journal of Immunopathology and Pharmacology. ,vol. 22, pp. 1135- 1141 ,(2009) , 10.1177/039463200902200432
A Arce-Salinas, J Guzmán, D Alarcón-Segovia, M H Cardiel, J Sánchez-Guerrero, Measurement of disease activity in systemic lupus erythematosus. Prospective validation of 3 clinical indices. The Journal of Rheumatology. ,vol. 19, pp. 1551- 1558 ,(1992)
P L Dobkin, D Choquette, M Zummer, A Beaulieu, E Rich, J R Goulet, J L Senécal, P R Fortin, D Da Costa, M A Fitzcharles, A E Clarke, Determinants of health status in fibromyalgia: a comparative study with systemic lupus erythematosus. The Journal of Rheumatology. ,vol. 27, pp. 365- 372 ,(2000)
J Thumboo, S P Chan, K Y Fong, M L Boey, S T Thio, P H Feng, K H Leong, A prospective study of factors affecting quality of life in systemic lupus erythematosus. The Journal of Rheumatology. ,vol. 27, pp. 1414- 1420 ,(2000)
J Gough, D D Gladman, A Ong, A MacKinnon, M B Urowitz, Lack of correlation among the 3 outcomes describing SLE: disease activity, damage and quality of life. Clinical and Experimental Rheumatology. ,vol. 14, pp. 305- 308 ,(1996)
K Mcelhone, J Abbott, L -S Teh, A review of health related quality of life in systemic lupus erythematosus Lupus. ,vol. 15, pp. 633- 643 ,(2006) , 10.1177/0961203306071710
Lynette Lim, Sam-ang Seubsman, Adrian Sleigh, Thai SF-36 health survey: tests of data quality, scaling assumptions, reliability and validity in healthy men and women Health and Quality of Life Outcomes. ,vol. 6, pp. 52- 52 ,(2008) , 10.1186/1477-7525-6-52
Vibeke Strand, Julian Thumboo, Health-related quality of life in patients with systemic lupus erythematosus: an update. Annals Academy of Medicine Singapore. ,vol. 36, pp. 115- 122 ,(2007)
Ricard Cervera, Munther A Khamashta, Josep Font, Gian Domenico Sebastiani, Antonio Gil, Paz Lavilla, Juan Carlos Mejía, A Olcay Aydintug, Hanna Chwalinska-Sadowska, Enrique de Ramón, Antonio Fernández-Nebro, Mauro Galeazzi, Merete Valen, Alessandro Mathieu, Frédéric Houssiau, Natividad Caro, Paula Alba, Manuel Ramos-Casals, Miguel Ingelmo, Graham RV Hughes, European Working Party on Systemic Lupus Erythematosus, None, Morbidity and mortality in systemic lupus erythematosus during a 10-year period: a comparison of early and late manifestations in a cohort of 1,000 patients Medicine. ,vol. 82, pp. 299- 308 ,(2003) , 10.1097/01.MD.0000091181.93122.55