True corrected seminal fructose level: a better marker of the function of seminal vesicles in infertile men.

作者: Gustavo F. Gonzales , Arturo Villena

DOI: 10.1046/J.1365-2605.2001.00306.X

关键词:

摘要: This study was designed to determine if the value obtained after multiplying motile sperm concentration by seminal fructose concentration, named true corrected fructose', correlates with motility in asthenozoospermic men. Forty-two male partners infertile couples were studied. Men treated 100 mg daily of clomiphene citrate for 5 days. Blood and semen samples collected before treatment 24 h end treatment. Serum testosterone, measured each subject. Corrected (log, multiplied fructose), fructose) values calculated. Prevalence asthenozoospermia 42.85% (18 42). hypofunction vesicles 9.5% using as a marker; 40.5% marker 47.6% vesicle function. Regression analysis showed better coefficient determination between (R 2 = 0.20, p < 0.001) than 0.05, 0.1) or 0.006, 0.5). Asthenozoospermia observed 22.7% subjects normal function vesicles, 65% men low (z 6.02, 0.0001). Multivariate that grade 3 improved increased (p 0.002). In those whose treatment, reduction prevalence from 50 28.6% 3.10, 0.002) whereas did not respond reduced 1.05; p: NS). conclusion, measurement relates cases asthenozoospermia. improves

参考文章(20)
Naomichi Okamura, Yutaka Tajima, Hiromichi Ishikawa, Shinichi Yoshii, Kenkichi Koiso, Yoshiki Sugita, Lowered levels of bicarbonate in seminal plasma cause the poor sperm motility in human infertile patients Fertility and Sterility. ,vol. 45, pp. 265- 272 ,(1986) , 10.1016/S0015-0282(16)49166-1
Gustavo F. Gonzales, Marco Garcia-Hjarles, Gustavo Velazquez, Juan Coyotupa, Seminal prolactin and its relationship to sperm motility in men. Fertility and Sterility. ,vol. 51, pp. 498- 503 ,(1989) , 10.1016/S0015-0282(16)60561-7
Shibabrata Biswas, Keith M. Ferguson, Jitka Stedronska, George Baffoe, Michael D. Mansfield, Madeleine H. Kosbab, Fructose and Hormone Levels in Semen: Their Correlations with Sperm Counts and Motility Fertility and Sterility. ,vol. 30, pp. 200- 204 ,(1978) , 10.1016/S0015-0282(16)43460-6
Claes Gottlieb, Kerstin Svanborg, Peter Eneroth, Marc Bygdeman, Effect of prostaglandins on human sperm function in vitro and seminal adenosine triphosphate content. Fertility and Sterility. ,vol. 49, pp. 322- 327 ,(1988) , 10.1016/S0015-0282(16)59723-4
Joseph H. Roe, A COLORIMETRIC METHOD FOR THE DETERMINATION OF FRUCTOSE IN BLOOD AND URINE Journal of Biological Chemistry. ,vol. 107, pp. 15- 22 ,(1934) , 10.1016/S0021-9258(18)75382-9
N Okamura, Y Tajima, A Soejima, H Masuda, Y Sugita, Sodium bicarbonate in seminal plasma stimulates the motility of mammalian spermatozoa through direct activation of adenylate cyclase. Journal of Biological Chemistry. ,vol. 260, pp. 9699- 9705 ,(1985) , 10.1016/S0021-9258(17)39295-5
N Okamura, Y Sugita, Activation of spermatozoan adenylate cyclase by a low molecular weight factor in porcine seminal plasma Journal of Biological Chemistry. ,vol. 258, pp. 13056- 13062 ,(1983) , 10.1016/S0021-9258(17)44079-8
E H Oliw, P Fahlstadius, M Hamberg, Isolation and biosynthesis of 20-hydroxyprostaglandins E1 and E2 in ram seminal fluid. Journal of Biological Chemistry. ,vol. 261, pp. 9216- 9221 ,(1986) , 10.1016/S0021-9258(18)67642-2
G. F. Gonzales, Corrected Seminal Fructose Test Archives of Andrology. ,vol. 33, pp. 17- 22 ,(1994) , 10.3109/01485019408987798
Gustavo F Gonzales, Amelia Salirrosas, Dicina Torres, Angela Sanchez, Arturo Villena, Use of clomiphene citrate in the treatment of men with high sperm chromatin stability Fertility and Sterility. ,vol. 69, pp. 1109- 1115 ,(1998) , 10.1016/S0015-0282(98)00090-9