Wnt/β-catenin signaling promotes differentiation, not self-renewal, of human embryonic stem cells and is repressed by Oct4

作者: R. J. Taylor , R. T. Moon , K. C. Davidson , A. M. Adams , J. M. Goodson

DOI: 10.1073/PNAS.1118777109

关键词:

摘要: … We hypothesized that if Wnt3A CM promotes loss of hESC maintenance through Wnt/β-catenin signaling, then we should be able to block this effect using downstream inhibitors of the …

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