Future Directions in Research on the Epigenetics of Aging
作者： Charles W. Caldwell , Huidong Shi
DOI: 10.1007/978-1-4419-0639-7_24
关键词:
摘要: Epigenetics of aging is a new research direction that brings exciting and in-depth revelations in the near future. As reviewed chapters throughout this book, likely to be influenced by many complex interacting epigenetic factors. These include DNA methylation, histone modifications, chromatin remodeling, noncoding RNAs. With help technologies, particularly knowledge derived from genome-wide epigenomic studies, upcoming years will an time make breakthroughs on epigenetics aging. Here we focus several directions overall their potential influence anti-aging intervention using personalized, epigenetic-targeted pharmacologic agents.
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Farahnaz Rahmatpanah, Pearlly S. Yan, Chuan Mu Chen, Charles W. Caldwell, Catherine Lofton-Day, Huidong Shi, Tim Hui Ming Huang, Expressed CpG island sequence tag microarray for dual screening of DNA hypermethylation and gene silencing in cancer cells. Cancer Research. ,vol. 62, pp. 3214- 3220 ,(2002)
Axel Schumacher, Philipp Kapranov, Zachary Kaminsky, James Flanagan, Abbas Assadzadeh, Patrick Yau, Carl Virtanen, Neil Winegarden, Jill Cheng, Thomas Gingeras, Arturas Petronis, Microarray-based DNA methylation profiling: technology and applications Nucleic Acids Research. ,vol. 34, pp. 528- 542 ,(2006) , 10.1093/NAR/GKJ461
R. A. Rollins, Large-scale structure of genomic methylation patterns Genome Research. ,vol. 16, pp. 157- 163 ,(2005) , 10.1101/GR.4362006
Claudia Gebhard, Lucia Schwarzfischer, Thu-Hang Pham, Elmar Schilling, Maja Klug, Reinhard Andreesen, Michael Rehli, Genome-Wide Profiling of CpG Methylation Identifies Novel Targets of Aberrant Hypermethylation in Myeloid Leukemia Cancer Research. ,vol. 66, pp. 6118- 6128 ,(2006) , 10.1158/0008-5472.CAN-06-0376
Florian Eckhardt, Joern Lewin, Rene Cortese, Vardhman K Rakyan, John Attwood, Matthias Burger, John Burton, Tony V Cox, Rob Davies, Thomas A Down, Carolina Haefliger, Roger Horton, Kevin Howe, David K Jackson, Jan Kunde, Christoph Koenig, Jennifer Liddle, David Niblett, Thomas Otto, Roger Pettett, Stefanie Seemann, Christian Thompson, Tony West, Jane Rogers, Alex Olek, Kurt Berlin, Stephan Beck, DNA methylation profiling of human chromosomes 6, 20 and 22 Nature Genetics. ,vol. 38, pp. 1378- 1385 ,(2006) , 10.1038/NG1909
Amy S Weinmann, Pearlly S Yan, Matthew J Oberley, Tim Hui-Ming Huang, Peggy J Farnham, Isolating human transcription factor targets by coupling chromatin immunoprecipitation and CpG island microarray analysis Genes & Development. ,vol. 16, pp. 235- 244 ,(2002) , 10.1101/GAD.943102
Huidong Shi, Sabine Maier, Inko Nimmrich, Pearlly S. Yan, Charles W. Caldwell, Alexander Olek, Tim Hui-Ming Huang, Oligonucleotide-based microarray for DNA methylation analysis: Principles and applications Journal of Cellular Biochemistry. ,vol. 88, pp. 138- 143 ,(2003) , 10.1002/JCB.10313
Manel Esteller, The necessity of a human epigenome project. Carcinogenesis. ,vol. 27, pp. 1121- 1125 ,(2006) , 10.1093/CARCIN/BGL033
Hans T Bjornsson, Martin I Sigurdsson, M Daniele Fallin, Rafael A Irizarry, Thor Aspelund, Hengmi Cui, Wenqiang Yu, Michael A Rongione, Tomas J Ekström, Tamara B Harris, Lenore J Launer, Gudny Eiriksdottir, Mark F Leppert, Carmen Sapienza, Vilmundur Gudnason, Andrew P Feinberg, Intra-individual Change Over Time in DNA Methylation With Familial Clustering JAMA. ,vol. 299, pp. 2877- 2883 ,(2008) , 10.1001/JAMA.299.24.2877
Gal-Yam Einav Nili, Yoshimasa Saito, Gerda Egger, Peter A. Jones, Cancer epigenetics: modifications, screening, and therapy. Annual Review of Medicine. ,vol. 59, pp. 267- 280 ,(2008) , 10.1146/ANNUREV.MED.59.061606.095816