A fetal-maternal shift in the oxygen equilibrium of hemoglobin from the viviparous caecilian,Typhlonectes compressicauda

摘要: 1. The equilibria and kinetics of oxygen binding by blood hemoglobin from adult fetal caecilians,Typhlonectes compressicauda, have been measured. 2. affinity is higher than that blood. 3. Electrophoresis hemoglobins suggests they may be identical: a major minor component occurs in each. 4. Adult identical equilibria. Stripped high no Bohr effect between pH 6.5 10.0. An “acid”, reversed present below 6.5. addition 1 mM ATP reduces the markedly produces moderate, normal effect. 5. nucleoside triphosphate erythrocytes adenosine triphosphate: about 10% triphosphates guanosine triphosphate. contain 3 times as much do erythrocytes. 6. to maternal shift equilibrium mediated entirely difference content red cells.