Paediatric heart transplantation

摘要: Abstract Paediatric heart transplantation is the last remaining treatment option for children in end-stage failure. Approximately 30 transplants are performed UK each year, between two specialist centres. two-thirds of recipients have suffered from a cardiomyopathy (mainly dilated), with remainder mainly being born congenital disease that is, or has become unamenable to conventional surgery. Over course 20 years, improvements surgical expertise, intensive care techniques and immunosuppressive strategies vastly improved outlook these children, it predicted majority grafts implanted today will at least 15 years. This inevitably means patients transplanted as young require retransplant during adolescence early adulthood, organ donation currently severely low levels, current chances second transplant poor. The goals programmes must therefore be postpone long possible careful management post-transplant phase, order improve longevity donated organs. article reviews practice paediatric UK.