Polymorphism of kidney pyruvate kinase in the mouse is determined by a gene, Pk-3, on chromosome 9

作者: Josephine Peters , H. R. Nash , Eva M. Eicher , Grahame Bulfield

DOI: 10.1007/BF00484007

关键词:

摘要: An electrophoretically detectable variant of pyruvate kinase (EC 2.7.1.40) has been found in the house mouse Mus musculus. The was seen all tissues examined except liver and red cells. gene (Pk-3) determining this electrophoretic variation is inherited as an autosomal codominant located on chromosome 9. Our data confirm that genetic determination cells separate from other tissues. In addition, our results indicate muscle (M1) kidney (M2) isozymes share at least one determinant may fact be determined by same structural gene.

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