Modeling of Nanoparticle-Mediated Electric Field Enhancement Inside Biological Cells Exposed to AC Electric Fields

作者: Pawan K. Tiwari , Sung Kil Kang , Gon Jun Kim , Jun Choi , A.-A. H. Mohamed

DOI: 10.1143/JJAP.48.087001

关键词:

摘要: We present in this article the effect of alternating electric field at kilohertz (kHz) and megahertz (MHz) frequencies on biological cells presence absence nanoparticles. The induced strength distribution region around cell membrane nucleus envelope display different behavior kHz MHz frequencies. attachment gold nanoparticles (GNPs), especially nanowires surface induce enhanced strengths. strengths are dependent length nanowire create varying regions when is increased from 2 to 4 µm. inside nucleoplasm adjacent cytoplasm. investigated a process electrostatic disruption across exceeds its tensile strength.

参考文章(24)
Jacob D. Gibson, Bishnu P. Khanal, Eugene R. Zubarev, Paclitaxel-functionalized gold nanoparticles. Journal of the American Chemical Society. ,vol. 129, pp. 11653- 11661 ,(2007) , 10.1021/JA075181K
I. Ermolina, Yu. Polevaya, Yu. Feldman, Analysis of dielectric spectra of eukaryotic cells by computer modeling European Biophysics Journal. ,vol. 29, pp. 141- 145 ,(2000) , 10.1007/S002490050259
Yugang Sun, Younan Xia, Shape-Controlled Synthesis of Gold and Silver Nanoparticles Science. ,vol. 298, pp. 2176- 2179 ,(2002) , 10.1126/SCIENCE.1077229
E.R. Adair, R.C. Petersen, Biological effects of radiofrequency/microwave radiation IEEE Transactions on Microwave Theory and Techniques. ,vol. 50, pp. 953- 962 ,(2002) , 10.1109/22.989978
G C Kim, G J Kim, S R Park, S M Jeon, H J Seo, F Iza, J K Lee, Air plasma coupled with antibody-conjugated nanoparticles: a new weapon against cancer Journal of Physics D. ,vol. 42, pp. 032005- ,(2009) , 10.1088/0022-3727/42/3/032005
Christopher Loo, Leon Hirsch, Min-Ho Lee, Emmanuel Chang, Jennifer West, Naomi Halas, Rebekah Drezek, Gold nanoshell bioconjugates for molecular imaging in living cells. Optics Letters. ,vol. 30, pp. 1012- 1014 ,(2005) , 10.1364/OL.30.001012
Prashant K. Jain, Ivan H. El-Sayed, Mostafa A. El-Sayed, Au nanoparticles target cancer Nano Today. ,vol. 2, pp. 18- 29 ,(2007) , 10.1016/S1748-0132(07)70016-6
Hargsoon Yoon, Devesh C Deshpande, Vasuda Ramachandran, Vijay K Varadan, Aligned nanowire growth using lithography-assisted bonding of a polycarbonate template for neural probe electrodes. Nanotechnology. ,vol. 19, pp. 025304- ,(2008) , 10.1088/0957-4484/19/02/025304
Stuart W. Prescott, Paul Mulvaney, Gold nanorod extinction spectra Journal of Applied Physics. ,vol. 99, pp. 123504- ,(2006) , 10.1063/1.2203212