Distinct metabolic flow enables large-scale purification of mouse and human pluripotent stem cell-derived cardiomyocytes.
作者： Shugo Tohyama , Fumiyuki Hattori , Motoaki Sano , Takako Hishiki , Yoshiko Nagahata
DOI: 10.1016/J.STEM.2012.09.013
关键词:
摘要: … and suggests that combining more sophisticated differentiation methods with our lactate method could facilitate realistic application of PSC-derived cardiomyocytes to human therapy. …
elsevier.com
core.ac.uk 
sci-hub.se 参考文章(30)
M G Klug, M H Soonpaa, G Y Koh, L J Field, Genetically selected cardiomyocytes from differentiating embronic stem cells form stable intracardiac grafts. Journal of Clinical Investigation. ,vol. 98, pp. 216- 224 ,(1996) , 10.1172/JCI118769
Tomofumi Tanaka, Shugo Tohyama, Mitsushige Murata, Fumimasa Nomura, Tomoyuki Kaneko, Hao Chen, Fumiyuki Hattori, Toru Egashira, Tomohisa Seki, Yohei Ohno, Uichi Koshimizu, Shinsuke Yuasa, Satoshi Ogawa, Shinya Yamanaka, Kenji Yasuda, Keiichi Fukuda, In vitro pharmacologic testing using human induced pluripotent stem cell-derived cardiomyocytes. Biochemical and Biophysical Research Communications. ,vol. 385, pp. 497- 502 ,(2009) , 10.1016/J.BBRC.2009.05.073
Tsunehiro Shintani, Takuya Iwabuchi, Tomoyoshi Soga, Yuichiro Kato, Takehiro Yamamoto, Naoharu Takano, Takako Hishiki, Yuki Ueno, Satsuki Ikeda, Tadayuki Sakuragawa, Kazuo Ishikawa, Nobuhito Goda, Yuko Kitagawa, Mayumi Kajimura, Kenji Matsumoto, Makoto Suematsu, Cystathionine β-synthase as a carbon monoxide-sensitive regulator of bile excretion Hepatology. ,vol. 49, pp. 141- 150 ,(2009) , 10.1002/HEP.22604
Pierre Sonveaux, Frédérique Végran, Thies Schroeder, Melanie C. Wergin, Julien Verrax, Zahid N. Rabbani, Christophe J. De Saedeleer, Kelly M. Kennedy, Caroline Diepart, Bénédicte F. Jordan, Michael J. Kelley, Bernard Gallez, Miriam L. Wahl, Olivier Feron, Mark W. Dewhirst, Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice Journal of Clinical Investigation. ,vol. 118, pp. 3930- 3942 ,(2008) , 10.1172/JCI36843
Shinsuke Yuasa, Yuji Itabashi, Uichi Koshimizu, Tomofumi Tanaka, Keijiro Sugimura, Masayoshi Kinoshita, Fumiyuki Hattori, Shin-ichi Fukami, Takuya Shimazaki, Hideyuki Okano, Satoshi Ogawa, Keiichi Fukuda, Transient inhibition of BMP signaling by Noggin induces cardiomyocyte differentiation of mouse embryonic stem cells. Nature Biotechnology. ,vol. 23, pp. 607- 611 ,(2005) , 10.1038/NBT1093
Nicole C Dubois, April M Craft, Parveen Sharma, David A Elliott, Edouard G Stanley, Andrew G Elefanty, Anthony Gramolini, Gordon Keller, SIRPA is a specific cell-surface marker for isolating cardiomyocytes derived from human pluripotent stem cells Nature Biotechnology. ,vol. 29, pp. 1011- 1018 ,(2011) , 10.1038/NBT.2005
David J Fisher, Michael A Heymann, Abraham M Rudolph, Myocardial Consumption of Oxygen and Carbohydrates in Newborn Sheep Pediatric Research. ,vol. 15, pp. 843- 846 ,(1981) , 10.1203/00006450-198105000-00003
John C Werner, Raymond E Sicard, Lactate metabolism of isolated, perfused fetal, and newborn pig hearts. Pediatric Research. ,vol. 22, pp. 552- 556 ,(1987) , 10.1203/00006450-198711000-00016
Fumiyuki Hattori, Hao Chen, Hiromi Yamashita, Shugo Tohyama, Yu-suke Satoh, Shinsuke Yuasa, Weizhen Li, Hiroyuki Yamakawa, Tomofumi Tanaka, Takeshi Onitsuka, Kenichiro Shimoji, Yohei Ohno, Toru Egashira, Ruri Kaneda, Mitsushige Murata, Kyoko Hidaka, Takayuki Morisaki, Erika Sasaki, Takeshi Suzuki, Motoaki Sano, Shinji Makino, Shinzo Oikawa, Keiichi Fukuda, None, Nongenetic method for purifying stem cell–derived cardiomyocytes Nature Methods. ,vol. 7, pp. 61- 66 ,(2010) , 10.1038/NMETH.1403
Arnoud C Fijnvandraat, Antoni CG Van Ginneken, Cees A Schumacher, Kenneth R Boheler, Ronald H Lekanne Deprez, Vincent M Christoffels, Antoon FM Moorman, Cardiomyocytes purified from differentiated embryonic stem cells exhibit characteristics of early chamber myocardium Journal of Molecular and Cellular Cardiology. ,vol. 35, pp. 1461- 1472 ,(2003) , 10.1016/J.YJMCC.2003.09.011