The toxicology of chromium with respect to its chemical speciation: A review
作者： Sidney A. Katz , Harry Salem
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摘要: The properties of trivalent and hexavalent chromium are reviewed with respect to acute chronic oral toxicity, dermal systemic toxicokinetics, cytotoxicity, genotoxicity carcinogenicity. compounds appear be 10-100 times more toxic than the when both administered by route. Dermal irritancy allergy frequently caused contact soluble compounds. cytotoxicity insoluble fibroblasts is 100-1000 greater that demonstrated In short-term tests, genotoxic effects four did Carcinogenicity appears associated inhalation less soluble/insoluble toxicology does not reside elemental form. It varies greatly among a wide variety very different Oxidation state solubility particularly important factors in considering toxicity its chemical speciation.
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