Massively parallel sequencing

作者: Yu-Hui Rogers , J. Craig Venter

DOI: 10.1038/437326A

关键词:

摘要: A sequencing system has been developed that can read 25 million bases of genetic code — the entire genome some fungi within four hours. The technique may provide an alternative approach to DNA sequencing. race is on for a big prize: job providing world's laboratories with successor ‘Sanger-based’ technology gave us first wave sequences. One in frame produced by 454 Life Sciences Corporation Branford, Connecticut. Today's reads 67,000 base pairs per hour; this new 100 times faster, reading 6 hour. improved performance results from using picolitre-sized chemical reactors, enhanced light-emitting chemistries and complex informatics. Further miniaturization planned. Such leaps one day make it possible analyse individual's before designing therapy: ultimate personalized medicine.

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