Genetic control of specific immune responses.

摘要: Publisher Summary This chapter discusses the genetic control of specific immune responses. The reviews recent important findings concerning “immune response genes” to antigenic determinants different amino acids. a antigen is complex process that must involve at various levels. fact factors are involved in stimulus has long been known. use synthetic polypeptide antigens played major role elucidating multiple genes described chapter. intriguing question what level these act remain be determined. Genetic and structural analysis normal immunoglobulins, myeloma proteins, antibodies produced great deal information about basis antibody structure but not yet given clear picture specificity. Structural proteins led similar conclusion for human mouse light chain. summarizes characteristic features common systems analyzes functions controlled by genes.”