Ultrasound-promoted efficient domino reaction for the one-pot synthesis of spiro-5-cyanopyrimidines: a rapid procedure
作者： Essam M. Hussein
DOI: 10.1007/S00706-013-1047-Y
关键词:
摘要: A novel and efficient protocol has been developed for the synthesis of various spiro-5-cyanopyrimidines via three-component condensation cyclic ketones, nitrile derivatives, thiourea or urea in ethanol at 60 °C using K2CO3 as catalyst under ultrasonic irradiation. In comparison to conventional methods, high yields, easy work-up, short reaction times are advantages this sonocatalyzed procedure. The effects catalyst, solvent, temperature were examined. .
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sci-hub.se 参考文章(21)
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