作者: Meral Görmen , Maité Sylla-Iyarreta Veitía , Fatma Trigui , Mehdi El Arbi , Clotilde Ferroud
DOI: 10.1016/J.JORGANCHEM.2015.07.016
关键词:
摘要: The antibacterial activity of bisacodyl, a drug used in therapeutic as laxative is described herein for the first time. Ten original ferrocenyl analogues have been synthesized via an efficient synthetic procedure using McMurry coupling reaction. was investigated against Gram-positive and Gram-negative foodborne pathogens including Listeria monocytogenes, Escherichia coli, Enterococcus faecalis, Salmonella enterica, Micrococcus luteus Staphylococcus aureus. results showed that most these compounds exhibit excellent antimicrobial activity, bisacodyl seemed to be more bactericides than bacteriostatic.