Genome-wide Occupancy Analysis by ChIP-chip and ChIP-Seq
作者： Hong Hao
DOI: 10.1007/978-1-4614-0631-0_96
关键词:
摘要: Interaction between protein complexes and the genome mediates essential functions including gene regulation, integrity, chromatin organization. Recent advances in immunoprecipitaion (ChIP)-chip ChIP-Seq technologies have enabled genome-wide identification of occupancy transcription factors modified histones that is critical for uncovering regulatory networks. This review discusses ChIP-chip technology, their pitfalls, insights from studies, applications pertaining to vertebrate retina.
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