Biological subtypes of breast cancer: Prognostic and therapeutic implications.

摘要: Breast cancer is a heterogeneous complex of diseases, spectrum many subtypes with distinct biological features that lead to differences in response patterns various treatment modalities and clinical outcomes. Traditional classification systems regarding characteristics may have limitations for patient-tailored strategies. Tumors similar pathological presentations different behaviors. Analyses breast new molecular techniques now hold promise the development more accurate tests prediction recurrence. Gene signatures been developed as predictors therapy protein gene products direct roles driving biology behavior cells are potential targets novel therapeutics. The present review summarizes current knowledge biology, focusing on prognostic predictive factors.